Sinusitis is a common condition that affects many women during lactation. Sinusitis is an inflammation of the nasal cavities, which causes a variety of symptoms, such as congestion, headaches, facial pain, and postnasal drip. While sinusitis can be treated effectively with medication, lactating women must be careful in choosing medicines to avoid any harm to their babies. In this article, we will discuss the best medicines to treat sinusitis in lactating women, including their uses, indications, contraindications, dosage, and side effects.
Best medicines for treating sinusitis in lactating women
1. Amoxicillin

Amoxicillin is a commonly prescribed antibiotic used to treat sinusitis caused by bacterial infections. Amoxicillin belongs to the penicillin family of antibiotics. Amoxicillin prevents the growth and multiplication of bacteria by inhibiting the bacteria’s ability to form cell walls, which are necessary for their survival. By blocking this process, amoxicillin effectively kills the bacteria and helps to reduce the infection.
Amoxicillin is considered safe for use during lactation and is widely prescribed by doctors. However, lactating women who are allergic to penicillin should avoid taking this medicine.
Dosage: The recommended dose is 500mg three times a day for 10 days.
Side effects: Common side effects include diarrhea, nausea, and vomiting. Allergic reactions are rare, but they can occur.
2. Cefuroxime

Like amoxicillin, cefuroxime is another antibiotic that is often used to treat sinusitis caused by bacterial infections. Cefuroxime works by killing the bacteria responsible for the infection. Cefuroxime interferes with the bacteria’s ability to form new cell walls. This disruption weakens the bacteria and makes them more susceptible to the body’s immune system and other antibiotics. This medicine is considered safe for use during lactation, but lactating women who are allergic to cephalosporins should avoid taking it.
Dosage: The recommended dose is 250mg to 500mg twice a day for 10 days.
Side effects: Common side effects include diarrhea, nausea, and vomiting. Allergic reactions are rare, but they can occur.
3. Azithromycin

Azithromycin is a macrolide antibiotic used to treat sinusitis caused by bacterial infections. Azithromycin works by inhibiting the bacteria’s ability to produce proteins. Proteins are essential for the bacteria’s survival and growth, so by blocking this process, azithromycin effectively kills the bacteria and helps to reduce the infection.
Azithromycin is generally considered safe for use during lactation, but lactating women who are allergic to macrolides should avoid taking this medicine.
Dosage: The recommended dose is 500mg once a day for 3 days.
Side effects: Common side effects include diarrhea, nausea, and vomiting. Allergic reactions are rare, but they can occur.
4. Pseudoephedrine

Pseudoephedrine is a decongestant used to relieve nasal congestion associated with sinusitis. This medicine works by constricting blood vessels in the nasal passages, which reduces swelling and congestion. Pseudoephedrine is considered safe for use during lactation, but lactating women with high blood pressure or heart disease should avoid taking this medicine.
Dosage: The recommended dose is 60mg four times a day.
Side effects: Common side effects include nervousness, restlessness, and insomnia. Pseudoephedrine can also increase blood pressure and heart rate.
5. Acetaminophen
Acetaminophen is a pain reliever and fever reducer used to alleviate the symptoms of sinusitis, such as headaches and facial pain. Acetaminophen works by blocking the production of chemicals (prostaglandins) in the body that cause pain and inflammation. By reducing these chemicals, acetaminophen helps to alleviate the symptoms of sinusitis, such as headache, fever, and body aches.
This medicine is considered safe for use during lactation, but lactating women should avoid taking more than the recommended dose.
Dosage: The recommended dose is 500mg to 1000mg every four to six hours.
Side effects: Common side effects include nausea, stomach pain, and liver damage if taken in excessive doses.
Medicines for treating sinusitis in lactating women
Sinusitis is a painful and uncomfortable condition, but with the right medication, it can be treated effectively. Lactating women must be careful about medicines they take to avoid any harm to their babies. The medicines mentioned in this article are considered safe for use during lactation, but it is always recommended to consult a doctor before taking any medication, because the doctor can provide individualized advice based on the woman’s medical history and other factors.
You should note that while these medications are generally considered safe, there is always a risk of side effects. You need to carefully read the medication label and follow the prescribed dosage to avoid any adverse effects. If any side effects or allergic reactions occur, you must stop taking the medication immediately and seek medical attention.
In addition to medication, there are other measures lactating women can take to alleviate the symptoms of sinusitis. These measures include using saline nasal sprays or rinses, applying warm compresses to the face, getting plenty of rest, and drinking lots of fluids.
Sources of information:
- American Academy of Pediatrics. (2020). The transfer of drugs and therapeutics into human breast milk: An update on selected topics. Pediatrics, 146(3), e20200575. https://doi.org/10.1542/peds.2020-0575
- Drugs.com. (n.d.). Amoxicillin. Retrieved March 17, 2023, from https://www.drugs.com/amoxicillin.html
- Drugs.com. (n.d.). Cefuroxime. Retrieved March 17, 2023, from https://www.drugs.com/cefuroxime.html
- Drugs.com. (n.d.). Azithromycin. Retrieved March 17, 2023, from https://www.drugs.com/azithromycin.html
- Drugs.com. (n.d.). Pseudoephedrine. Retrieved March 17, 2023, from https://www.drugs.com/pseudoephedrine.html
- Drugs.com. (n.d.). Acetaminophen. Retrieved March 17, 2023, from https://www.drugs.com/acetaminophen.html